The brown powder inside the puffballs fungi is used to treat weeping sores when there are no bandages to cover the area. The powder is also used on burns when the blister has broken and the burn area is weepy. The powder is dusted over the affected area. It will dry the area so infection does not set in.
Source: Andre, Alestine, Nan t'aih nakwits'inahtsìh (The Land Gives Us Strength) (2006)